Keiko Agena has continued acting on television, appearing in various popular shows over the years. In the years following the end of "Gilmore Girls," Agena had one-episode arcs in "Private Practice" in 2007, "House" in 2010, and "Scandal" in 2012. This was followed by a three-episode arc in "Shameless" in 2013 (via IMDb).

A few years later, in 2017, she landed a more prominent role in the Netflix teen drama series "13 Reasons Why," in which she played teacher Pam Bradley. Then, in 2018, she had a main role in the Hulu drama series "The First," which chronicles a team of astronauts preparing to go to Mars. In the same year, Agena also had a recurring role in the first season of "Dirty John," showing up in four of the eight episodes.

In 2019, Agena began her run as a primary cast member on "Prodigal Son," in which she plays NYC medical examiner Edrisa Tanaka. And finally, Agena had a recurring role on AMC's "Better Call Saul" where she played paralegal, Viola Goto.