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| 23 Nov 2022 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 20,000 | $30.48 | $609,600 23 Nov 2022 | 1,870,356 | ↗ |
| 1 Nov 2022 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 20,000 | $30.27 | $605,400 1 Nov 2022 | 1,890,356 | ↗ |
| 28 Sep 2022 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 20,000 | $30.82 | $616,400 28 Sep 2022 | 1,910,356 | ↗ |
| 23 Aug 2022 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 20,000 | $31.61 | $632,200 23 Aug 2022 | 1,930,356 | ↗ |
| 25 Jul 2022 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 20,000 | $35.61 | $712,200 25 Jul 2022 | 1,950,356 | ↗ |
| 23 Mar 2022 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 20,000 | $33.83 | $676,600 23 Mar 2022 | 2,024,370 | ↗ |
| 28 Dec 2021 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 63,131 | $44.43 | $2,804,910 28 Dec 2021 | 78,848 | ↗ |
| 7 Jun 2021 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Option | 94,378 | $18.70 | $1,764,869 7 Jun 2021 | 2,638,748 | ↗ |
| 21 May 2021 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 46,763 | $60.11 | $2,810,924 21 May 2021 | 2,542,296 | ↗ |
| 3 May 2021 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 3,237 | $60.11 | $194,576 3 May 2021 | 2,589,059 | ↗ |
| 1 Apr 2021 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 50,000 | $56.62 | $2,831,000 1 Apr 2021 | 2,592,296 | ↗ |
| 1 Mar 2021 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 100,000 | $66.22 | $6,622,000 1 Mar 2021 | 2,642,296 | ↗ |
| 16 Jun 2020 | DNLIDenali Therapeutics Inc | Marc Tessier Lavigne Director | Sale | 400,000 | $26.10 | $10,440,000 16 Jun 2020 | 2,739,043 | ↗ |
| 29 Sep 2022 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 10,838 | $413.33 | $4,479,671 29 Sep 2022 | 5,881 | ↗ |
| 21 Mar 2022 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 7,439 | $380.95 | $2,833,887 21 Mar 2022 | 9,708 | ↗ |
| 16 Mar 2022 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 12,191 | $375.77 | $4,581,012 16 Mar 2022 | 10,099 | ↗ |
| 9 Dec 2021 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 3,784 | $371.40 | $1,405,378 9 Dec 2021 | 5,862 | ↗ |
| 13 Sep 2021 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 12,750 | $273.67 | $3,489,293 13 Sep 2021 | 14,828 | ↗ |
| 6 May 2020 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 15,000 | $177.82 | $2,667,300 6 May 2020 | 16,830 | ↗ |
| 13 Feb 2020 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 14,279 | $53.08 | $757,929 13 Feb 2020 | 11,109 | ↗ |
| 5 Aug 2015 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 5,000 | $57.11 | $285,550 5 Aug 2015 | 6,187 | ↗ |
| 26 Feb 2015 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 3,000 | $50.91 | $152,730 26 Feb 2015 | 4,187 | ↗ |
| 26 Aug 2014 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 4,387 | $50.91 | $223,342 26 Aug 2014 | 4,187 | ↗ |
| 6 May 2013 | REGNRegeneron Pharmaceuticals, Inc. | Marc Tessier Lavigne Director | Option | 13,334 | $53.23 | $709,769 6 May 2013 | 300 | ↗ |
| 24 Jul 2013 | AGIOAgios Pharmaceuticals Inc | Marc Tessier Lavigne Director | Buy | 55,555 | $18.00 | $999,990 24 Jul 2013 | 101,009 | ↗ |
