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| 17 Nov 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 17 Nov 2023 | 368,670 | ↗ |
| 17 Oct 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 17 Oct 2023 | 368,670 | ↗ |
| 18 Sep 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 18 Sep 2023 | 368,670 | ↗ |
| 15 Sep 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 15 Sep 2023 | 368,670 | ↗ |
| 21 Jul 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 49,779 | $2.67 | $132,910 21 Jul 2023 | 367,420 | ↗ |
| 20 Jul 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 50,000 | $2.67 | $133,500 20 Jul 2023 | 317,641 | ↗ |
| 17 Jul 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 17 Jul 2023 | 268,891 | ↗ |
| 20 Jun 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 20 Jun 2023 | 268,891 | ↗ |
| 17 May 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 17 May 2023 | 268,891 | ↗ |
| 17 Apr 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 17 Apr 2023 | 268,891 | ↗ |
| 17 Mar 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 17 Mar 2023 | 268,891 | ↗ |
| 17 Feb 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 17 Feb 2023 | 268,891 | ↗ |
| 17 Jan 2023 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 17 Jan 2023 | 268,891 | ↗ |
| 15 Dec 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 15 Dec 2022 | 265,024 | ↗ |
| 15 Nov 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 15 Nov 2022 | 265,024 | ↗ |
| 14 Oct 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 14 Oct 2022 | 265,024 | ↗ |
| 15 Sep 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 15 Sep 2022 | 265,024 | ↗ |
| 15 Aug 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 15 Aug 2022 | 265,024 | ↗ |
| 15 Jul 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 15 Jul 2022 | 265,024 | ↗ |
| 15 Jun 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 15 Jun 2022 | 265,024 | ↗ |
| 16 May 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 16 May 2022 | 265,024 | ↗ |
| 14 Apr 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 14 Apr 2022 | 265,024 | ↗ |
| 15 Mar 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 15 Mar 2022 | 260,794 | ↗ |
| 15 Feb 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 15 Feb 2022 | 675,024 | ↗ |
| 14 Jan 2022 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 1,250 | $2.67 | $3,338 14 Jan 2022 | 675,024 | ↗ |
| 15 Dec 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 3,000 | $2.67 | $8,010 15 Dec 2021 | 672,544 | ↗ |
| 4 Nov 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 6,000 | $2.67 | $16,020 4 Nov 2021 | 672,544 | ↗ |
| 16 Aug 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 16 Aug 2021 | 672,044 | ↗ |
| 15 Jul 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 Jul 2021 | 672,044 | ↗ |
| 15 Jun 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 Jun 2021 | 672,044 | ↗ |
| 14 May 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 14 May 2021 | 672,044 | ↗ |
| 21 Apr 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 21 Apr 2021 | 672,044 | ↗ |
| 15 Mar 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 Mar 2021 | 672,044 | ↗ |
| 16 Feb 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 16 Feb 2021 | 672,044 | ↗ |
| 15 Jan 2021 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 Jan 2021 | 672,044 | ↗ |
| 15 Dec 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 Dec 2020 | 672,044 | ↗ |
| 16 Nov 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 16 Nov 2020 | 672,044 | ↗ |
| 15 Oct 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 Oct 2020 | 672,044 | ↗ |
| 7 Oct 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 7,500 | $2.67 | $20,025 7 Oct 2020 | 677,044 | ↗ |
| 15 Jun 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 Jun 2020 | 672,044 | ↗ |
| 15 May 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 May 2020 | 672,044 | ↗ |
| 15 Apr 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 Apr 2020 | 672,044 | ↗ |
| 25 Mar 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 25 Mar 2020 | 672,044 | ↗ |
| 14 Feb 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 14 Feb 2020 | 672,044 | ↗ |
| 15 Jan 2020 | APLSApellis Pharmaceuticals Inc | Alec Machiels Director | Option | 2,500 | $2.67 | $6,675 15 Jan 2020 | 672,044 | ↗ |
